Site Audit Isavuconazole ( 241479-67-4 )and Intermediates

2018-09-11
 

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API: Isavuconazonium sulfate   

CAS:946075-13-4

Chemical Formula: C35H36F2N8O9S2 
Molecular Weight: 814.84 
Elemental Analysis: C, 51.59; H, 4.45; F, 4.66; N, 13.75; O, 17.67; S, 7.87

 

Structural formula:

 

 

  Part one : Isavuconazole( 241479-67-4 )and Intermediates  

 

Product name:Isavuconazole

CAS:241479-67-4

Chemical Formula: C22H17F2N5OS 
Exact Mass: 437.1122 
Molecular Weight: 437.4688 
Elemental Analysis: C, 60.40; H, 3.92; F, 8.69; N, 16.01; O, 3.66; S, 7.33

 

Structural formula:

 

We have more than1kg in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 

 

 

➤ Acalabrutinib Intermeidtaes:

 

1.Name:(2R,3R)-2-(2,5-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

cas:241479-72-1

 

Structural formula:

We have more than2.5kg in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 

 

2.Name:QYOWWJNQQPRWCO-QPUJVOFHSA-N

CAS:241479-73-2

Structural formula:

We have more than1.5kg in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 

 

 

3.Name:SYSUFNUKZJVPBI-TVQRCGJNSA-N

CAS:241479-74-3

Structural formula:

We have more than1.2kg in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 

 

 

 

4.Name: (2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)

butanethioamide  cas:368421-58-3

Structural formula:

We have more than2.3kg in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 

 

 

5.Name: [2-(methylamino)pyridin-3-yl]methanol

CAS:32399-12-5

Structural formula:

We have more than2.6kg in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 

 

 

6.Name:(2-(Methylamino)pyridin-3-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate

CAS:1180002-01-0

Structural formula:

We have more than1.7kg in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 

 

 

 

7.Name:(2-(((1-Chloroethoxy)carbonyl)(methyl)amino)pyridin-3-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate

CAS:338990-31-1

Structural formula:

We have more than1.9kg in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 

 

 

 

 

Contact information:

EOS Med Chem, Medchem is Big

執大象,天下往,往而無害,安平泰

 

WEB: www.eosmedchem.com

 

EMAIL: info@eosmedchem.com; eosmedchem@gmail.com; eosmedchem@qq.com  

TEL: 0086-531-69905422

GMP PLANT: No. 37, Yulong Road, Qufu City, Shandong Province.

 

            Part two:  Isavuconazole impurities           

 

➤➤Isavuconazole impurities :

 

Isavuconazole Impurity1

 

Isavuconazole Impurity2

 

Isavuconazole Impurity3

 

Isavuconazole Impurity4

 

Isavuconazole Impurity5

 

Isavuconazole Impurity6

 

 

 

Isavuconazole Impurity7

 

Isavuconazole Impurity8

 

Isavuconazole Impurity9

 

Isavuconazole Impurity10

 

 

 

Isavuconazole Impurity11

 

Isavuconazole Impurity12

 

Isavuconazole Impurity13

 

Isavuconazole Impurity14

 

Isavuconazole Impurity15

 

Isavuconazole Impurity16

 

Isavuconazole Impurity17

 

Isavuconazole Impurity18

 

Isavuconazole Impurity19

 

Isavuconazole Impurity20

 

Isavuconazole Impurity21

 

Isavuconazole Impurity22

 

Isavuconazole Impurity23

 

 

Isavuconazole Impurity24

 

Isavuconazole Impurity25

 

Isavuconazole Impurity26

 

Isavuconazole Impurity27

 

Isavuconazole Impurity28

 

Isavuconazole Impurity29

 

Isavuconazole Impurity30

 

 

Follow EOS to learn more about Acalabrutinib 241479-67-4    

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